CURRICULUM VITAE

March 1995

NAME: Jack Willard Buchanan, Jr.

PHONE: Memphis VA Medical Center (901) 523-8990 ext 6698; University of Tennessee, Memphis (901) 448-7200; Home (901) 278-8791

BIRTHDATE: August 21, 1945

BIRTHPLACE: Crossville, Tennessee

MARITAL STATUS: Married to Frances A. Tylavsky, RD, MS, DrPH, Assistant Professor of Biostatistics and Epidemiology and Preventive Medicine, University of Tennessee, Memphis

CHILDREN: Christopher William Buchanan, born June 14, 1984

Elizabeth Lugin Buchanan, born November 13, 1986

EDUCATION:

High School:

Clark County High School, Winchester KY, May, 1963

Undergraduate:

University of Kentucky, Lexington KY, July 1963-August 1967, BS in Electrical Engineering, December 20, 1967

Graduate/Medical School:

University of Kentucky, Lexington KY, September 1967-December 1969, MS in Electrical Engineering, August 11, 1970

University of Kentucky, Lexington KY, July 1971-June 1975, MD, June 7, 1975

Honors:

University of Kentucky Medical Student Research Award, 1975

Midwest Student Research Forum Award, Columbia MO, 1975

Internship:

Straight Medicine, University of Texas at Houston Affiliated Hospitals, Houston TX, July 1975- June 1976

Residency:

Internal Medicine, University of Kentucky Affiliated Hospitals, Lexington KY, July 1976-June 1977, July 1978-June 1979

Postgraduate:

NIH Individual National Research Fellow, Division of Cardiology, University of Kentucky, Lexington, KY, July 1977-June 1978

NIH Research Fellow, Division of Cardiology, University of North Carolina Chapel Hill NC, November 1980-June 1982

MEDICAL LICENSURE:

Kentucky, 18541, August 27, 1976 (inactive)

North Carolina, 24894, March 7, 1981

SOCIETY MEMBERSHIPS:

American Heart Association Council on Basic Sciences

American Physiological Society

Cardiac Electrophysiological Society

Institute of Electrical and Electronics Engineers

IEEE Computer Society

IEEE Engineering in Medicine and Biology Society

International Society for Heart Research

Biophysical Society

Memphis Society for Biomedical Engineering

American Medical Informatics Association

UNIVERSITY APPOINTMENTS:

Biomedical Engineer, Division of Cardiology, Department of Medicine, University of Kentucky, Lexington KY, September 1967-June 1975

Research Assistant Professor of Medicine, University of North Carolina, Chapel Hill NC, July 1982-November 1990

Research Assistant Professor, Biomedical Engineering and Mathematics Curriculum, University of North Carolina, Chapel Hill NC, July 1982-November 1990

Associate Professor (Primary Appointment), Department of Biomedical Engineering, College of Graduate Health Sciences, University of Tennessee, Memphis TN, October 1990-

Associate Professor (Joint), Department of Medicine, College of Medicine, University of Tennessee, Memphis TN, October 1990-

Associate Professor (Joint), Department of Health Informatics, College of Graduate Health Sciences, University of Tennessee, Memphis TN, October 1990-

Assistant Professor (Joint), Department of Physiology, College of Medicine, University of Tennessee, Memphis TN, April 1991-

Adjunct Associate Professor of Biomedical Engineering, University of North Carolina, Chapel Hill, NC, April 1991-March 1994

Adjunct Faculty Member, Department of Biomedical Engineering, Herff College of Engineering, University of Memphis, Memphis, TN, July 1994-

CLINICAL APPOINTMENTS:

Mary Chiles Hospital, Mt. Sterling KY, Attending Physician (Active), Emergency Associates of Mt Sterling PSC, July 1979-October 1981

North Carolina Memorial Hospital, Chapel Hill NC, Attending Physician (Active), July 1982- November 1990

Veterans Affairs Medical Center, Memphis, TN, Staff Physician (Cardiology), (Active) October 1990-

OTHER APPOINTMENTS:

Faculty Computing Director, Biomedical Engineering and Mathematics Curriculum, University of North Carolina, Chapel Hill NC, July 1987-September 1990

Biosensor Systems Director, Duke-North Carolina-National Science Foundation Engineering Research Center for Emerging Cardiovascular Technologies, Duke University, Durham NC, April 1988-June 1990

Co-Director (with Benjamin MW Tsui), Advanced Biomedical Computing and Display Facility, Biomedical Engineering and Mathematics Curriculum, University of North Carolina, Chapel Hill NC, February 1989-September 1990

Co-Director (with BG Thompson), Biomedical Engineering Communications Research Facility, Biomedical Engineering and Mathematics Curriculum, University of North Carolina, Chapel Hill NC, January 1990-September 1990

Director, Biomedical Engineering Distributed Computing Research Environment, Department of Biomedical Engineering, University of Tennessee, Memphis TN, November 1990-

Director, Electrocardiographic Laboratory, Veterans Affairs Medical Center, Memphis TN, July 1992-

Faculty Director, Biomedical Instrumentation Division, University of Tennessee, Memphis August 1991-

Director, Memphis Educational Computer Connectivity Alliance (MECCA), Memphis TN August 1992-

Advisory Committee, Department of Health Information Management, University of Tennessee, Memphis, August 1994-

TEACHING EXPERIENCE (See also, Fellows/Graduate Students Trained)

Full member, graduate faculty, University of North Carolina, Chapel Hill, NC, 1982-90

Full member (Level 3), graduate faculty, University of Tennessee, Memphis, TN, 1991-

Adjunct member, graduate faculty, The University of Memphis, Memphis, TN, 1994-

University of North Carolina at Chapel Hill:

Course Director and Principal Lecturer, Biomedical Instrumentation, Graduate Level, 3 Hours Credit, 7 Times (1982-1990), 6-10 students each offering

Course Director and Principal Lecturer, Bioelectricity, Graduate Level, 3 Hours Credit, 2 Times (1982-1990) 2-4 students each offering

University of Tennessee, Memphis:

Course Director and Principal Lecturer, Biomedical Instrumentation, Graduate Level, 4 Hours Credit, 4 Times (1991-1994), 3-8 students each offering

Course Director and Principal Lecturer, Introduction to Biomedical Engineering, Graduate Level, 4 Times (1990-1993, 4-8 students each offering

Course Director, Student Seminar, Graduate Level, Fall, 1992

Course Director, Clinical Internship, Graduate Level, Summer 1992, Summer 1993

PUBLICATIONS (Book Chapters):

1. Gettes LS, Hill JL, Buchanan JW. Future directions of cardiac electrophysiology. In Progress in Cardiology, vol 10, edited by PN Yu, JF Goodwin. Philadelphia, Lea and Febiger, 1984:361-371

2. Gettes LS, Buchanan JW Jr, Saito T, Kagiyama Y, Oshita S, Fujino T. Studies concerned with slow conduction. In Cardiac Electrophysiology and Arrhythmias, edited by DP Zipes, J Jalife. Orlando, Grune and Stratton, 1985:81-87

3. Kusy RP, Buchanan JW. Quality control of cardiovascular wire plunge electrodes. In Microbeam Analysis--1989, edited by P.E. Russel. San Francisco, San Francisco Press, 1989;63-64

4. Buchanan JW, Gettes LS. Ionic Environment and Propagation In Cardiac Electrophysiology: From Cell to Bedside, edited by DP Zipes, J Jalife. Orlando, WB Saunders, 1990:149-156

5. Buchanan JW, Fujino T. Ventricular muscle as a functionally continuous medium for electrical propagation:experiments and simulations. In Imaging, Analysis and Simulation of the Cardiac System, edited by S Sideman, R Beyar. London, Freund Publishing House, 1990:699-717

PUBLICATIONS (Journals and Proceedings):

*peer reviewed

*1. Lasseter KC, Buchanan JW Jr, Yoshonis KF. A mechanism for 'false' inhibition of demand pacemakers. Circulation 1970;42:1093-1097

*2. Buchanan JW Jr, Shabetai R. The true power dissipation of catheter tip velocity probes. Cardiovascular Research 1972;6:211-213

*3. Wyatt RH, Kotchen JM, Hochstrasser DL, Buchanan JW Jr, Campbell DR, Slaughter JC, Doll AH. An epidemiologic study of blood screening tests and illness histories among chemical workers involved in the manufacture of polyvinyl chloride.Annals of the New York Academy of Sciences 1975;246:80-87

*4. Saito S, Chen CM, Buchanan JW Jr, Gettes LS, Lynch MR Steady state and time dependent slowing of conduction in canine hearts: effects of potassium and lidocaine. Circulation Research 1978;42:246-253

*5. Buchanan JW Jr, Saito T, Gettes LS. The effects of antiarrhythmic drugs, stimulation frequency, and potassium induced resting membrane potential changes on conduction velocity and dV/dtmax in guinea pig myocardium. Circulation Research 1985;56:696-703

*6. Buchanan JW Jr, Oshita S, Fujino T, Gettes LS. A method for the measurement of internal longitudinal resistance in papillary muscle. American Journal of Physiology 1986;251(Heart and Circulatory Physiology 20):H210-H217

*7. Watanabe I, Johnson TA, Buchanan J, Engle CL, Gettes LS. Effect of graded coronary flow reduction on ionic, electrical and mechanical indices of ischemia in the pig. Circulation 1987;76:1127-1134

*8. Cascio WE, Foster JR, Buchanan JW Jr, Johnson TA, Gettes LS. Enhancement of procainamide-induced rate-dependent conduction slowing by elevated myocardial extracellular potassium concentration in vivo. Circulation 1987;76:1380-1387

*9. Johnson TA, Coronel R, Graebner CA, Buchanan JW, Janse MJ, Gettes LS. Relationship between extracellular potassium accumulation and local TQ-segment potential during acute myocardial ischemia in the porcine heart. Journal of Molecular and Cellular Cardiology 1987;19:947-952

*10. Cascio WE, Woelfel AK, Knisley SB, Buchanan JW Jr, Foster JR, Gettes LS. Use-dependence of amiodarone during the sinus tachycardia of exercise in coronary artery disease. American Journal of Cardiology 1988;61:1042-1045

*11. Hiramatsu Y, Buchanan JW, Knisley SB, Gettes LS.Rate-dependent effects of hypoxia on internal longitudinal resistance in guinea pig papillary muscles. Circulation Research 1988;63:923-929

*12. Hiramatsu Y, Buchanan JW Jr, Knisley SB, Koch GG, Kropp S, Gettes LS. Role of rate dependent uncoupling on conduction change during simulated ischemia in guinea pig papillary muscles--effect of verapamil. Circulation Research 1989;65:95-102

*13. Ash RB, Wortman JJ, Nagle HT, Buchanan JW. Silicon based electrode arrays. Proceedings of the 11th Annual International Conference, IEEE Engineering in Medicine and Biology Society,

1989;210-211

*14. Buchanan J, Thompson BG. Opportunities for the use of broad-band packet-switched data networks for direct patient care. In Proceedings of the Third Annual IEEE Symposium on Computer-Based Medical Systems. Los Alamitos, CA, IEEE Computer Society Press, 1990;9-13

*15. Buck RP, Buchanan JW, Kusy RP. Technology based systems:chemistry, physics, materials science and engineering of chemical sensors/ biosensors for in vivo applications. Proceedings of the 12th Annual International Conference, IEEE Engineering in Medicine and Biology Society, 1990;637-638

*16. Knisley SB, Maruyama T, Buchanan JW Jr. Interstitial potential during propagation in bathed ventricular muscle. Biophysical Journal 1991;59:509-515

*17. Muller-Borer BJ, Erdman DJ, Buchanan JW. Discrete bioelectric model of ventricular tissue. Proceedings of the 13th Annual International Conference, IEEE Engineering in Medicine and Biology Society, 1991;510-511

*18. Maruyama T, Cascio WE Knisley SB, Buchanan J, Gettes LS. Effects of ryanodine and BAY K 8644 on membrane properties and conduction during simulated ischemia. American Journal of Physiology 1991;261(Heart and Circulatory Physiology 30):H2008-H2015

19. Buchanan JW. Effects of regional membrane changes on propagation in a model of ventricular muscle. Proceedings of the 11th Southern Biomedical Engineering Symposium 1992;20-21

*20. Muller-Borer BJ, Erdman DJ, Buchanan JW. Electrical coupling and impulse propagation in anatomically modeled ventricular tissue. IEEE Transactions on Biomedical Engineering 1994;41:445-454

PUBLICATIONS (Abstracts):

*1. Buchanan JW Jr, Chen CM, Saito S, Gettes LS. Time dependent effects of hyperpotassemia on conduction in intact dog hearts. Circulation 1975;52:II-18

2. Saito S, Buchanan JW Jr, Chen CM, Gettes LS. Time dependent effects of hyperpotassemia on conduction in intact dog hearts. Clinical Research 1975;23:513A

3. Buchanan JW Jr, Gettes LS, Chen CM. Steady state and time dependent effects of systemic hyperkalemia on conduction in the intact heart. Clinical Research 1975;23:548A

*4. Saito T, Buchanan JW Jr, Gettes LS, Hill JL. Determinants of conduction velocity in guinea pig papillary muscle at varying K concentrations. Circulation 1978;58:II-45

*5. Buchanan JW Jr, Saito T, Kagiyama Y, Hill JL, Gettes LS. The relationship between upstroke velocity and conduction in guinea pig myocardium. American Journal of Cardiology 1982;49:983

*6. Oshita S, Buchanan J, Gettes LS. A method for studying internal longitudinal resistance in guinea pig papillary muscles. Circulation 1982;66:II-233

*7. Oshita S, Buchanan J, Gettes LS. Effect of changes in K+ and pH on internal longitudinal resistance in ventricular fibers. Circulation 1982;66:II-233

*8. Buchanan JW Jr, Gettes LS. Steady state and rate dependent effects of antiarrhythmic drugs on Vmax and conduction velocity in guinea pig papillary muscle. Circulation 1983;68:III-295

9. Fujino T, Buchanan JW Jr, Gettes LS. Effects of high K+, acidosis, hypoxia and glucose lack on internal longitudinal resistance in ventricular muscle. The Physiologist 1984;27:217

*10. Fujino T, Buchanan JW Jr, Gettes LS. Effect of simulated ischemia on cell-to-cell coupling in ventricular muscle:influence of verapamil. Circulation 1984;70:II-348

*11. Fujino T, Buchanan JW Jr, Gettes LS. Effects of verapamil on the changes in conduction time, Vmax and longitudinal resistance induced by simulated ischemia. Circulation 1985;72:III-236

*12. Johnson TA, Buchanan JW Jr, Gettes LS, Graebner C, Janse MJ, Coronel R. K+-TQ relationships following coronary occlusion in the isolated porcine heart. Circulation 1985;72:III-27

13. Buchanan JW Jr, Fujino T. Propagation in guinea pig papillary muscle appears to fit continuous cable theory in the presence of apparent cellular uncoupling. Federation Proceedings 1986;45:28

*14. Cascio W, Buchanan J, Simpson R, Woelfel A, Gettes L, Foster J. Use-dependence of amiodarone during sinus tachycardia of exercise. Circulation 1986;74:II-213

*15. Buchanan JW Jr, Fujino T. Effects of lateral coupling resistance on longitudinal electrical discontinuities in a multicellular ventricular muscle model. Circulation 1986;74:II-418

16. Hiramatsu Y, Buchanan JW Jr, Gettes LS. Frequency dependent increase in longitudinal resistance in guinea pig ventricular muscle exposed to hypoxia. Federation Proceedings 1987;46:335

17. Quint SR, Simpson RJ Jr, Buchanan JW, Corcoran MC. The effect of nitroglycerin on heart period variability in humans. Federation Proceedings 1987;46:673

18. Buchanan J. Effects of lateral interconnections on the longitudinal propagation characteristics of the heart. In Proceedings of the First North Carolina Workshop on Bioelectronics. Research Triangle Park, North Carolina Biotechnology Center, September 1987

19. Buchanan JW. Effects of the distribution of lateral connections between cell columns in a two dimensional ventricular muscle model: the importance of subcellular resolution in simulations of multicellular tissue. The Physiologist 1987;30:177

*20. Hiramatsu Y, Buchanan JW, Knisley SB, Gettes LS. Frequency dependent increase in longitudinal resistance in guinea pig ventricular muscle exposed to hypoxia. Circulation 1987;76:IV-114

21. Hiramatsu Y, Knisley S, Buchanan J, Gettes L. Role of rate dependent uncoupling on conduction change during simulated ischemia in guinea pig papillary muscles-effect of verapamil. The FASEB Journal 1988;2:A930

22. Kusy RP, Engle C, Buchanan JW. Failure analysis of biosensors. Proceedings of the 2nd Annual North Carolina ACS Section Symposium: Chemistry at Surfaces and Interfaces, Duke University, September 1988

23. Knisley S, Hiramatsu Y, Buchanan J, Gettes L. Comparison of theoretical and observed conduction changes during simulated ischemia in ventricular muscle. Biophysical Journal 1989;55:293a

*24. Hiramatsu Y, Buchanan JW Jr, Knisley SB, Gettes LS. Rate-dependent cellular uncoupling contributes to conduction changes in acute ischemia and is prevented by verapamil. Journal of the American College of Cardiology 1989;13:127a

25. Kusy RP, Engle C, Buchanan JW, Whitley JQ, Reinbold KA. Failure analysis and modification of cardiovascular biosensors. Transactions of the 15th Annual Meeting of the Society for Biomaterials, Orlando, FL 1989;12:38

26. Kusy RP, Whitley JQ, Buchanan JW. Fundamental problems associated with the manufacture, transport, and use of miniature K+ and pH electrodes. Proceedings of American Institute of Chemical Engineering National Meeting on Materials of Biomedical Application, Philadelphia, PA, August 1989

*27. Boyd LM, Engle CL, Martin DG, Buchanan JW, Knisley SB, Gettes LS. Assessment of local injury current by potassium equilibrium and injury potential relationships during acute myocardial ischemia. Circulation 1989;II-501

28. Maruyama T, Knisley S, Buchanan J, Gettes L. Ryanodine suppresses conduction slowing, decrease of Vmax, and cellular uncoupling induced by simulated ischemia. The FASEB Journal 1990;4:A681

*29. Knisley SB, Maruyama T, Buchanan JW. Interstitial potential in ventricular fibers. Circulation 1990;III-643

*30. Maruyama T, Sun W, Buchanan JW, Gettes LS. Resting membrane potential-independent depression of Vmax by acute ischemia: role of internal calcium. Circulation 1990;III-745

31. Cardoso S, Newman K, Garrett E, Romano S, Buchanan J. Circadian profiles of heart rate variability (H.R.V.) in controls and in heart transplant recipients. Clinical Research 1992;40:863A

32. Newman K, Cardoso S, Smith B, Perry J, Garcia C, Buchanan J, Karas J. Analysis of heart rate variability in survivors of sudden cardiac death. Clinical Research 1992;40:863A

33. Romano S, Buchanan JW, Newman KP, Kundich RC, Gaber O, Garrett HE, Cardoso SS. Circadian patterns of heart rate variability in heart transplant patients, diabetes mellitus with severe organ damage, and normal volunteers. Clinical Research 1993;41:719A

34. Newman KP, Bradley J, Buchanan J, Jordan JM, Perry BS, Garrett HE, Cardoso SC, Karas JG, Coombs D, Duvall D, Kundich RC. Power spectrum analysis of heart rate variability in the transplanted heart: Assessment of the range of normal values. Clinical Research 1993;41:721A

COMMITTEES AND OFFICES HELD:

Extramural:

Member, Research Review Subcommittee, North Carolina Affiliate, American Heart Association, Chapel Hill, NC, (July 1988-June 1990)

Consultant, Surgery and Biomedical Engineering Study Section National Heart Lung and Blood Institute, NIH, 1989

Editorial Consultant, Circulation Research, 1986-

Editorial Consultant, American Journal of Physiology, 1985-

Editorial Consultant, IEEE Transactions in Biomedical Engineering, 1991-

Editorial Consultant, Journal of Biomedical Engineering, 1993-

Member, Special Study Section 8 (Small Business Innovative Research), National Institutes of Health, Division of Research Grants, 1992

Member, Network Infrastructure for Education Review and Policy Panel, Education and Human Resources and Computer and Information Science and Engineering Directorates, National Science Foundation, 1994, 1995

Member, NSFnet Connections Review Panel, Computer and Information Science and Engineering Directorate, National Science Foundaton, 1994

Member, Experimental Program to Stimulate Competitive Research: Experimental Systemic Initiative Grants Review Panel, Education and Human Resources Directorate, National Science Foundation, 1995

Interinstitutional:

Member, Steering Committee, Duke-North Carolina-National Science Foundation Engineering Research Center for Emerging Cardiovascular Technologies, 1987-1990

Director, Memphis Educational Computer Connectivity Alliance (A consortium involving the University of Tennessee, Memphis, Memphis State University, Lemoyne-Owen College, Christian Brothers University, Rhodes College, Memphis City Schools, State Technical Institute, Shelby State Community College, Memphis Public Library and The University of Tennessee Affiliated Hospitals), 1992-

Member, Urban Systemic Initiative for Math, Science and Technology Advisory Committee and "Partnerships and Collaborations" Subcommittee, Memphis City Schools, 1994-

University of North Carolina:

Microelectronics Affiliated Programs Committee (1983-1990)

Office of Video and Data Communications Advisory Committee (1988-1990)

University of North Carolina, School of Medicine:

Technical Liaison, School of Medicine Office of Information Systems (1987-1990)

Biomedical Engineering Representative, Health Promotion/Disease Prevention (1987-1990)

University of North Carolina, Curriculum in Biomedical Engineering:

Computer Committee (Chairman 1987-1990)

Examination Committee (Member 1984-1987, Chairman 1986-1987)

Research Committee (Member 1984-1990)

Student Recruitment Committee (Member 1984-1989)

University of Tennessee, Memphis, College of Graduate Health Sciences:

Committee on Health Informatics Curriculum (1991-93)

Faculty Search Committee, Comparative Medicine (1992-93)

Faculty Search Committee, Biomedical Engineering (Chairman, 1990, Member 1992, Co- Chairman 1995)

Faculty Search Committee, Biostatistics and Epidemiology (1993)

University of Memphis

Faculty Search Committee, Biomedical Engineering (1995)

Veterans Affairs Medical Center, Memphis, Tennessee

Automated Information Systems Advisory Committee (1991- ) Vice Chairman (1992-

Clinical Computing ad hoc Planning Committee Co-Chairman (1993-

FELLOWS/GRADUATE STUDENTS TRAINED:

Takao Fujino, MD, visiting scientist from Kyushu University, Fukuoka, Japan, July 1985-June 1987 (jointly with Dr. Leonard Gettes), Present address: Department of Laboratory Medicine, Oita Medical University, Oita, Japan

Stephen B. Knisley, PhD, Doctoral Committee Chairman and Advisor for PhD in Biomedical Engineering, awarded June, 1988.Dissertation title: "Action Potential Propagation and

Electrical Properties in Ventricular Muscle: Effects of Ischemia.", Present address: Department of Medicine, Duke University, Durham, NC

Barbara Muller-Borer, MS, PhD, Doctoral Committee Chairman and Advisor for PhD in Biomedical Engineering, awarded December, 1991. Dissertation title: "The Effects of Cellular

Uncoupling on Action Potential Propagation in Ventricular Tissue: A Computer Modeling and Simulation Study", Present address: Departments of Medicine and Biomedical Engineering,

University of North Carolina, Chapel Hill, NC

Served as a committee member for the following Biomedical Engineering students:

PhD:

David R Gilland, PhD, 1989, "An investigation of maximum likelihood-EM image reconstruction in single photon emission computed tomography"

Damon C Smith, PhD, 1988, "Noninvasive assessment of the mechanical input impedance of human skeletal muscle"

Melissa C Corcoran, PhD, 1987, "A nonlinear analysis of cardiorespiratory control"

Karen T Randall, PhD, 1987, "Multicompartmental cerebrospinal fluid system model: dynamic interaction of regulatory mechanisms"

Geoffrey W Hilliard, MD, PhD, 1986, "Design of a video rate multi-processor based computing system for the calculation of two-dimensional fast Fourier transformations"

MS:

Robert C. Kundich, University of Tennessee, Memphis

Chandrasekhar Ramanathan, MS, 1990, "Fast maximum liklihood estimation in SPECT image reconstruction"

J Glen Ballard Jr, MS, 1989, "Quantitation in SPECT: an evaluation of several reconstruction techniques"

Tsong-Tseh Tsay, MS, 1986, "Left ventricular volume determination using single photon emission computed tomography"

Hai-Ping Wu, MS, 1985, "Pattern recognition for bacterial detection and classification in multiparameter flow cytometry"

Participated in the training of numerous clinical and research fellows in the University of North Carolina Division of Cardiology (approximately 20 over 8 years)

RESEARCH AND OTHER EXTERNAL SUPPORT:

1. "Active and Passive Factors Affecting Action Potential Propagation in Cardiac Muscle" Grant-in-Aid, Principal Investigator, July 1 1977-June 30 1978, Kentucky Heart Association

2. "Comparison of Conduction of Rapid and Slow Channel Dependent Action Potentials in Ventricular Muscle", Grant-in-Aid, Principal Investigator, July 1 1981-June 30 1982, NC Affiliate, American Heart Association

3. "Factors Influencing Conduction Velocity in Ventricular Myocardium", Grant-in-Aid, Principal Investigator, July 11982-June 30 1985, NC Affiliate, American Heart Association

4. "Effects of Ischemia and Drugs on Conduction", Co-Investigator, 30% effort, part of NIH Program Project Grant "Mechanisms of Sudden Cardiac Death", LS Gettes, Program Project Director, July 1 1982-June 30 1987, U S Public Health Service, NHLBI

5. "Electronics Core", Principal Investigator, 30% effort, part of NIH Program Project Grant "Mechanisms of Sudden Cardiac Death", LS Gettes, Program Project Director, July 1 1982-June 30 1987, U S Public Health Service, NHLBI

6. "Effects of Coupling on Propagation in Ventricular Muscle", Principal Investigator, 30% effort, part of NIH Program Project Grant "Mechanisms of Sudden Cardiac Death", LS Gettes, Program Project Director, July 1 1987-June 30 1992, U S Public Health Service, NHLBI

7. "Electronics Core", Principal Investigator, 10% effort, part of NIH Program Project Grant "Mechanisms of Sudden Cardiac Death", LS Gettes, Program Project Director, July 1 1987-June 30 1992, U S Public Health Service, NHLBI

8. "Biosensor Systems", Principal Investigator, 16% effort, part of Duke, North Carolina, National Science Foundation Engineering Research Center for Emerging Cardiovascular Technologies, T Pilkington, Center Director, October 1 1987-September 30 1992, North Carolina Biotechnology Center and National Science Foundation

9. "Advanced Biomedical Computing and Display Facility", Co-Principal Investigator, February 1 1989-January 31 1990, Shared Instrument Grant, U S Public Health Service, NIH Div of Research Resources

10. "Memphis Educational Computer Communications Alliance (MECCA)" Principal Investigator, January 1, 1993-December 30, 1995, National Science Foundation, NCR-9221562 $55,000 to UT Memphis (includes Memphis State and East High School as well); $20,000 to LeMoyne-Owen College; $20,000 to Christian Brothers University; $20,000 to Rhodes College

11. "A new construct for interpreting the fundamental dilemma of insufficient tissue perfusion during sustained gravitational acceleration" Co-Principal Investigator, January 1, 1993-December 31, 1993, U S Air Force, Office of Scientific Research, $20,000

12. "Assessment of Autonomic Nervous System Function in Heart Transplant Recipients: Investigation of a new Noninvasive Technology to Diagnose Rejection" Co-Investigator, December 1, 1992-November 30, 1995, Baptist Memorial Hospital Clinical Innovation fund, $59,320.

13. Supplement to "Memphis Educational Computer Communications Alliance (MECCA)" Principal Investigator, April 1, 1994-March 31, 1995, Division of Education and Human Resources. National Science Foundation. $263,304.

Pending:

14. "Point of Care Clinical Information System" Project Leader, January 1, 1995-September 30, 1996, Department of Veterans' Affairs Hospital Open System Technology program. $249,900.

MAJOR INVITED PRESENTATIONS

1. "Ventricular Muscle as a Functionally Continuous Medium for Electrical Propagation: Experiments and Simulations" 5th Henry Goldberg International Workshop on Analysis and Simulation of the Cardiac System­Inhomogeneity and Imaging, April 10-14, 1988, Cambridge England. Invited by Technion-Israel Institute of Technology, Haifa, Israel and Rutgers State Universiy of New Jersey, Piscataway, New Jersey, USA

2. "A Municipal Area Network for Education" Association for Computing Machinery Special Interest Group on University Computing and Computer Services Annual Meeting, St. Louis, MO, March 1993

3. "Memphis Educational Computer Connectivity Alliance: Example of Networking Infrastructure for Education, a new NSF Initiative" National Net '94 Policy Conference, April 6-8, 1994, Washington DC. Invited by Applications of Advanced Technology Section, Education and Human Resources Directorate, National Science Foundation, Washington, DC

PRACTICE (PROFESSIONAL) EXPERIENCE:

Organizor and Partner, Emergency Services of Mt. Sterling, PSC, Mt. Sterling, KY, July 1979- October 1980